# Survival Rate for Patients with Pulmonary Arterial Hypertension (PAH)

Survival Rate for Patients with Pulmonary Arterial Hypertension (PAH)

This Demonstration determines the survival rate over time for patients with pulmonary arterial hypertension (PAH) for nonresponders to calcium channel blockers and responders to calcium channel blockers based on the patient's mean pulmonary artery pressure, mean right atrial pressure, and cardiac index. PAH is a progressive disease characterized by the initial blockage and later destruction of the pulmonary arteries that directly causes right ventricular failure and death. The multivariate survival equations used in this Demonstration predict a patient's chance of survival over a period of time and are based on exponential regression analysis. The pulmonary hypertension connection (PHC) equations or the survival equations are , where for nonresponders to calcium channel blockers and for responders to calcium channel blockers. In these equations, is the probability of patient survival, is the time in years, is the mean pulmonary artery pressure (mmHg), is the mean right atrial pressure (mmHg), and is the cardiac index ().

P(t)=

-A(x,y,z)t

e

A(x,y,z)=

(-1.270-0.0148x+0.0402y-0.361z)

e

A(x,y,z)=

(-3.012-0.0148x+0.0402y-0.361z)

e

P(t)

t

x

y

z

L×

-1

min

-2

m