# Pharmacokinetic Two-Compartment Model

Pharmacokinetic Two-Compartment Model

In the pharmacokinetic two-compartment model, the rate coefficients are determined by the physiology and the specific drug properties. In order to establish a desired drug level in compartment 2 (blue line) the size and the frequency of the dosage are the available variables. The reactions are taken to be first-order reactions. After entering appropriate values for the rate coefficients and desired target drug levels, these variables are adjusted to achieve the desired result. Clinical studies are used to obtain values of these constants for each drug regime.