WOLFRAM|DEMONSTRATIONS PROJECT

Minimal Hodgkin-Huxley Model: DC Stimulus

​
applied current
6.3
sodium equilibrium potential
115
potassium equilibrium potential
-12
membrane capacitance
leakage channel conductance
Electrical properties of neurons are described by the Hodgkin–Huxley (HH) model with multiple phenomenological parameters. They include the axon-membrane capacitance and the equilibrium potentials and conductances for sodium, potassium, and leakage channels. A signature of an HH neuron is the spiking membrane-voltage response to a stimulus current above a threshold. This Demonstration plots the "action potential" response, and shows that it is robust even in the absence of membrane capacitance or leakage channels, or a significant variation in the equilibrium potentials for the sodium (potassium) channel, shown by the top (bottom) dashed red line.