Temperature Distribution in Four-Layer Skin Tissue

​
temperature along tissue depth
​
​
​
volumetric heat generation, W/
3
m
100
distance along tisssue length, m
0
heater length, % tissue length
50.
distance along tissue depth, m
0.01675
This Demonstration models the temperature distribution of four skin layers subjected to an external heat source. Human skin is modeled as a four-layer structure consisting of the epidermis, the dermis, the subcutaneous tissue and an internal tissue. Assume that each layer is homogeneous, and assume that blood perfusion, thermal conductivity and heat capacity are constant in each layer. Assume also that the layers are perfectly bonded to each other to enable a continuous flow of heat across the interfaces.

Details

Two-dimensional steady-state heat transfer in biological tissue is governed by the Pennes bioheat equation[1]:
2
∂
T
∂
2
x
+
2
∂
T
∂
2
y
+
ωρ
C
p
k
(T-
T
b
)+
q
m
k
+
q
ext
k
=0
with boundary conditions:
∂T(0,y)
∂x
=
∂T(L,y)
∂x
=0
,
∂T(x,0)
∂y
=Q
,
T(x,H)=
T
b
and
Q=
-
q
ext
k
e
L/2(1-f/100)≤x<L/2(1+f/100)
0
L/2(1+f)<x<L/2(1-f/100).
Here:
L
and
H
are the length and depth of the skin, respectively
f
is the length of the heating source expressed as a percent of the skin length
x
and
y
are the skin length and depth coordinates, respectively
T
and
T
b
represent the skin and blood temperatures, respectively
ω
is the blood perfusion rate per unit volume
C
p
is the blood heat capacity
k
is the skin thermal conductivity
k
e
is the thermal conductivity of the epidermis
q
is the metabolic heat generation
q
ext
is the heat generation due to an external source
Q
is an expression for the quantity of heat and the length of the heat source as a percent of the length of the skin
These equations are solved with the built-in Mathematica function NDSolve, using a different set of parameters
ωρ
C
p
k
,
q
m
k
,
q
ext
k
for each skin layer.
You can vary the intensity and length of the external heat source
Q
and the location in the skin
x
and
y
to determine the temperature distribution of the skin tissue.

References

[1] F. Xu, T. J. Lu, K. A. Seffen and E. Y. K. Ng, "Mathematical Modeling of Skin Bioheat Transfer," Applied Mechanics Reviews, 62(5), 2009 050801. doi:10.1115/1.3124646.

Permanent Citation

Clay Gruesbeck
​
​"Temperature Distribution in Four-Layer Skin Tissue" from the Wolfram Demonstrations Project http://demonstrations.wolfram.com/TemperatureDistributionInFourLayerSkinTissue/​
​Published: January 10, 2020
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