Liquid Chromatography Simulation

select model

partition

adsorption

select plotting function

normal

integral

number of plates

50

transit time

20

component 1 (red)

component 2 (blue)

X

1

50

X

2

50

K

1

1.

K

2

2.

X

s

1

10

X

s

2

10

b

1

20

b

2

20

time scale

1

input width

1

This Demonstration expands on the Demonstration "Liquid Chromatography with Linear Adsorption Equilibrium and Plate Model". Using a discrete plate representation of the chromatographic column, it includes both linear (partition) and nonlinear (noncompetitive Langmuir adsorption) models. The column throughput rate is accounted for by the addition of a first-order exponential modification of the basic models. Frontal analysis as well as preparative chromatography can also be simulated.